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Related post: days they may be dusted with iodoform. In no instance
have I detected any purulent exudation. Ordinarily, within
a few days the grafts are firmly united, and can not be de-
tached without using force. They present a reddish hue
for some time, which gradually fades out, and after several
weeks the line of demarkation is scarcely seen.
The operation may be rendered absolutely painless by I
Dec. 12, 18»1.|
injectino- a few drops of a cocaine solution. This does
not interfere with the vitality of the graft. The only in- Methotrexate Calculator
convenience I have found is a slight tumefaction of the
part, which interferes with Methotrexate Generic perfectly Methotrexate Tablets 2.5mg accurate coaptation.
This may be obviated by the cataphoretic introduction of
cocaine or by general anaesthesia.
In the last operation upon this patient the person
furnishing the grafts insisted upon being etherized, and, in
order to get through with him as Methotrexate 50mg soon as possible, I re-
moved six grafts in succession, and, instead of immediately
inserting each one as it was removed, I placed them Methotrexate 10 Mg in a
solution of salt and tepid water for several minutes. This
delay did not affect the result, as they all united })romptly
and perfectly. I learn from a letter received from the pa-
tient a few days ago (September Fda Methotrexate l7th) that the hairs fell
out from this last series of grafts and have not been repro-
duced. He further says : " There are some hairs growing in
the former grafts. No doubt about that. I Generic Methotrexate will say I
would very gladly go on with the operation if I could be
assured of success in the end." No further operative
measures have been attempted owing to the impossibility of
securing suitable material, as the patient's hair is difficult
to match in tint and texture. Another serious difficulty
was encountered in obtaining a sufficiently deep bed in
the thinned contracted scar tissue in which to insert the
While the operation in this case has not yielded the Methotrexate Fda
most brilliant result, so far as a cure of the deformity is
concerned, it has demonstrated the fact that it is perfectly
practicable to ingraft deep sections of skin containing the
follicular apparatus, preserving the integrity of their ana-
tomical structure as well as their functions. Unfortu-
nately, in small grafts the changes inseparable from the
processes of union and cicatrization cause more or less
contraction of Methotrexate 10mg the transplanted tissues and tend to oblit-
erate the hair follicles, more especially in the peripheral
margin of the graft. This destructive Methotrexate 5mg change is less mani-
fest in the central portion, which would Methotrexate 2.5mg Tablets justify the as-
sumption that a graft of- considerable area would in all
probability produce an abundant and \'igorous growth of hair.
The most available material for grafting an extensive Methotrexate Alternatives sur-
face would be the scalp of a person recently deceased.
The punch used in this case was about 35 to 40 mm.
in circumference. A slightly smaller instrument was em-
ployed in preparing the receptacle, owing to the tendency
of the button of tissue to contract. I have not used larger
instruments, because the person furnishing the material
stipulated that the resulting scars should not be readily
perceptible. I Order Methotrexate am persuaded that much larger grafts
would unite just as readily and perfectly. Rectangular or
other shaped instruments might be used if desired.
The demonstration Methotrexate 15mg of the practicability of successfully
grafting deep sections of the skin with the complete conser-
vation of the integrity of the follicular structures has, on ac-
count of the necessary limitations of its employment, a curi-
ous rather than a practical interest. If this were its only, or
indeed its chief, value, I should not have trespassed upon
the valuable time of this association by describing it in de-
tail. The method has, in my opinion, a much more valua-
ble application. I believe that it constitutes Methotrexate 15 Mg an ideal treat-
ment Methotrexate 20 Mg for circumscribed malignant and papillary growths
occurring upon the face, where cosmetic considerations play
an important rdle in determining the choice of an operation.
Small epitheliomata, lupus nodules, moles, warts, and other
facial blemishes may be removed and pieces of smooth,
liealthy skin substituted with the absolute certainty, if the
operation is Methotrexate Infection carefully done, of securing immediate union
without the puckered, disfiguring scars which follow cutting
and cautery o])erations. In one case where I removed a
small epithelioma above the right superciliary ridge and re-
placed it with tissue from the Alternatives To Methotrexate patient's arm, the operation
was entirely successful. After the lapse of several months
there has been no recurrence of the disease. The line of
union is scarcely traceable, and it would be difficult to iden-
tify the new tissue. (This patient was exhibited.)
The operation is more especially indicated in epithelio- Methotrexate Brand
mata of recent development and limited area when the can-
cerous infiltration has not invaded the surrounding tissues.
Even when Methotrexate 50 Mg the disease is more extensive, the epithelioma-
tous nodules around the edge may be punched out one by

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